Luna Lab for RNA Systems Virology Dept. of Biochemistry & RNA Center, Case Western Reserve University

Unraveling viral secrets through RNA biology

The Luna Lab is a team of molecular biologists and virologists dedicated to understanding how RNA-binding proteins orchestrate cellular responses during viral infections. We use RNA viruses as tools to uncover fundamental principles of RNA biology and develop potential therapeutic strategies for viral diseases and RNA-related disorders. We employ diverse toolkits including reverse genetics, functional genomics, advanced RNA profiling techniques, and innovative subcellular imaging methods. Current work focuses on mapping the dynamic spatial interactions between viral genomes and host factors, decoding the regulatory logic of RNA-protein networks, and developing novel tools to study RNA biology at unprecedented resolution.

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